Sandra has tried out 'proper' acting on many occasions, not least in 1996's In Love and War, when Richard Attenborough chose her as his leading lady, a nurse who falls in love with Ernest Hemingway in the First World War. Her leading man was the then star Chris O'Donnell.
The Depressive
Typical of the 'woman's film' that has popped up here and there in Sandra's career, Hope Floats saw her battling depression in her hometown and finding love in the guise of Harry Connick Jr.
One of Sandra's most under-rated offerings saw her star opposite Ben Affleck in this offbeat romcom, playing a kooky plane traveller who gets stranded with Ben on the way to his wedding.
Arguably Sandra's most challenging role to date, 28 Days saw her playing an alcoholic who is forced to check into rehab where she inevitably finds love - this time with The Wire's Dominic West.
She may not have technically won a personal statuette, but a plum role in the award-winning Crash in 2005 saw her get up on stage when it won a host of Academy Awards. She impressed as the hypertense wife of DA Brendan Fraser whose rite-of-passage underlined the zeitgeisty feel of the movie.
In an unusual casting choice Sandra played the role of reclusive author Harper Lee, the best friend of Truman Capote in the 'other' biopic of the wild American author, and again showed that with the right direction she is capable of showing a lot of depth.
More than a decade after Speed made them internationally famous, Sandra reunited with Keanu Reeves for this romantic and mythical feature. Some found it confusing, but others loved it.