In medicine, an emotional state characterized by sadness, unhappy thoughts, apathy, and dejection. Sadness is a normal response to major losses such as bereavement or unemployment. After childbirth,
postnatal depression is common. Clinical depression, which is prolonged or unduly severe, often requires treatment, such as
antidepressant medication,
cognitive therapy, or, in very rare cases,
electroconvulsive therapy (ECT), in which an electrical current is passed through the brain.
Periods of depression may alternate with periods of high optimism, over-enthusiasm, and confidence. This is the manic phase in a disorder known as
manic depression or
bipolar disorder. A manic depressive state is one in which a person switches repeatedly from one extreme to the other. Each mood can last for weeks or months. Typically, the depressive state lasts longer than the manic phase.
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